Bacillus thuringiensis Cry1A toxins divert progenitor cell fate toward enteroendocrine lineage by diminishing cell adhesion with intestinal stem cells
R. JNEID, R. LOUDHAIEF, N. ZUCCHINI-PASCAL, M.-P. NAWROT-ESPOSITO, A. FICHANT, R. ROUSSET, M. BONIS, D. OSMAN, A. GALLET
This study shows Cry1A toxins from Btk disrupt cell adhesion in Drosophila, causing progenitor cells to differentiate into enteroendocrine cells instead of enterocytes.
bioRxiv · Apr 13, 2022Cell Biology