A Trio of Ubiquitin Ligases Sequentially Drive Ubiquitylation and Autophagic Degradation of Dysfunctional Yeast Proteasomes
R. S. Marshall, R. D. Vierstra
The paper shows that three ubiquitin ligases sequentially ubiquitylate dysfunctional yeast proteasomes to enable their autophagic degradation.
bioRxiv · May 12, 2021Cell Biology