Identification, Characterization, and Targeting of a Rare and Temporal Dendritic Cell State that Facilitates Adaptive Immune Responses
P. E. Deak, B. Studnitzer, R. Steinhardt, A. Esser-Kahn
This study identifies a rare, temporally-controlled dendritic cell state that enhances adaptive immune responses by activating neighboring cells through paracrine signaling and shows that targeting specific receptors on these cells improves vaccine efficacy.
bioRxiv · Oct 8, 2020 · PreprintImmunology