R. Stelkens

Wild Patagonian yeast improve the evolutionary potential of novel interspecific hybrid strains for Lager brewing

This study improves Lager yeast hybrids using wild Patagonian S. eubayanus strains, revealing genetic factors that enhance fermentation and aroma profiles.

Adaptation to complex environments reveals pervasive trade-offs and genomic targets with large pleiotropic effects

This study shows that adaptation to complex environments involves trade-offs and pleiotropic effects, with mutations affecting multiple biological processes and recurrent gene targets.

Hybrid adaptation is hampered by Haldane's sieve

The paper shows that hybrid yeast adaptation is slowed by Haldane's sieve due to slower loss of heterozygosity and incomplete dominance of adaptive mutations.

The dynamics of adaptation to stress from standing genetic variation and de novo mutations

This study tracks fitness and genomic changes in yeast populations under stress using experimental evolution, showing rapid adaptation and parallel genetic changes.

Recombining your way out of trouble: The genetic architecture of hybrid fitness under environmental stress

This study investigates hybrid fitness in yeast under environmental stress, finding selection against heterozygosity and positive epistasis between divergent species.