Differential activation of parathyroid and renal Ca2+-sensing receptors underlies the renal phenotype in autosomal dominant hypocalcemia 1
W. van Megen, R. Tan, R. T. Alexander, H. Dimke
This study shows that parathyroid and renal Ca2+-sensing receptors have different activation thresholds in ADH1, explaining why some patients have low PTH without hypercalciuria.
bioRxiv · Feb 1, 2021 · PreprintPhysiology