Author

R. T. Loewen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:imaging· 1 Organism:non-human primate· 1

Frequent Co-Authors

C. Wang· 3 shared S. Waxman· 3 shared Y. Dang· 3 shared N. Loewen· 2 shared M. Sun· 1 shared N. A. Loewen· 1 shared P. Shah· 1 shared X. Xia· 1 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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3 shared papersCell Biology

C. Wang

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3 papers

Recent·Most cited

Ripasudil in a model of pigmentary glaucoma

C. Wang, Y. Dang, S. Waxman, Y. Hong, P. Shah, R. T. Loewen, X. Xia, N. Loewen

This study evaluates Ripasudil's effects on pigmentary glaucoma in a porcine model, showing reduced trabecular meshwork stress fibers, restored phagocytosis, and normalized intraocular pressure.

bioRxiv · May 4, 2020Pharmacology & Toxicology

Intraocular pressure elevation precedes a phagocytosis decline in a model of pigmentary glaucoma

Y. Dang, S. Waxman, C. Wang, R. T. Loewen, N. A. Loewen

This study shows that intraocular pressure elevation occurs before phagocytosis decline in a porcine model of pigmentary glaucoma, indicating separate mechanisms for these phenomena.

bioRxiv · Aug 13, 2017Cell Biology

A porcine ex vivo model of pigmentary glaucoma

Y. Dang, S. Waxman, C. Wang, R. T. Loewen, M. Sun, N. Loewen

This study develops a porcine ex vivo model of pigmentary glaucoma, showing intraocular hypertension, pigment accumulation, and impaired phagocytosis in trabecular meshwork cells, with RhoA identified as a key regulator.

bioRxiv · Aug 11, 2017Cell Biology