ImmunologybioRxiv
Alopecia areata patients show deficiency of FOXP3+CD39+ T regulatory cells and clonotypic restriction of Treg TCR?-chain, which highlights the immunopathological aspect of the disease
A. B. M. Astrand, F. N. Hamed, M. Bertolini…·R. Tazi-Ahnini
The paper examines Treg cell subsets and TCRβ clonotypes in alopecia areata patients, finding reduced FOXP3+CD39+ Tregs and specific clonotypic differences that suggest potential therapeutic targets.
DOI 10.1371/journal.pone.0210308