Cancer BiologybioRxivPreprint
VRK1 is a Paralog Synthetic Lethal Target in VRK2-methylated Glioblastoma
J. A. Shields, S. R. Meier, M. Bandi…·N. Emmanuel
This study identifies VRK1 as a synthetic lethal target in VRK2-methylated glioblastoma by showing that VRK1 inhibition leads to tumor growth inhibition in xenograft models.
DOI 10.1101/2021.12.30.474571