Effect of SARS-CoV-2 spike mutations on its activation by TMPRSS2 and TMPRSS13
A. Stevaert, R. Van Berwaer, V. Raeymaekers, M. Laporte, L. M. J. Naesens
This study investigates how mutations in the SARS-CoV-2 spike protein's S2 motif affect activation by TMPRSS2 and TMPRSS13 proteases, finding that K814 is dispensable for TMPRSS2 but not TMPRSS13.
bioRxiv · Jan 26, 2022 · PreprintMicrobiology