Glutamate transporters contain a conserved chloride channel with two hydrophobic gates
I. Chen, S. Pant, Q. Wu, R. Cater, M. Sobti, R. Vandenberg, A. G. Stewart, E. Tajkhorshid, J. Font, R. M. Ryan
The paper reports the cryo-EM structure of a glutamate transporter homologue, revealing a conserved chloride channel with two hydrophobic gates that facilitates dual-function transport.
Nature · Feb 17, 2021Peer-reviewedBiophysics