Author

R. W. Shuai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein sequence· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Liu· 1 shared C. A. Huynh· 1 shared C. Niu· 1 shared H. R. Lee· 1 shared J. A. Ruffolo· 1 shared J. J. Gray· 1 shared J. Wen· 1 shared J. Wu· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

B. Liu

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2 papers

Recent·Most cited

BioengineeringbioRxivDec 13, 2021

Generative language modeling for antibody design

R. W. Shuai, J. A. Ruffolo, J. J. Gray

This paper introduces IgLM, a generative language model for designing synthetic antibody sequences with improved developability.

DOI 10.1016/j.cels.2023.10.001

humanprotein sequence

𝕏 PostBluesky

ImmunologybioRxivPreprintSep 7, 2021

TET1 controls Cxcl1 induction by DNA demethylation and promotes neutrophil recruitment during acute lung injury

K. M. Yee, R. W. Shuai, B. Liu…·K. Shuai

This study shows TET1 facilitates DNA demethylation of the Cxcl1 promoter, enabling its induction and neutrophil recruitment during acute lung injury.

DOI 10.1101/2021.09.07.459280

mousebulk RNA-seq

𝕏 PostBluesky