Author

R. Y. Moreno

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

B. Lu· 1 shared C. R. Vakoc· 1 shared L. A. Benjamin· 1 shared M. J. Weiss· 1 shared O. E. Demerdash· 1 shared O. Klingbeil· 1 shared R. Feng· 1 shared S. A. Polyanskaya· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

B. Lu

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1 paper

Recent·Most cited

Cancer BiologybioRxivMay 9, 2021

The SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia

S. A. Polyanskaya, R. Y. Moreno, B. Lu…·C. R. Vakoc

This study identifies the SCP4-STK35/PDIK1L phosphatase-kinase complex as a critical signaling dependency in AML, showing its role in proliferation and amino acid metabolism through dual regulatory mechanisms.

DOI 10.1016/j.celrep.2021.110233

humangenetic perturbation / CRISPR