Computational model of 3D cell migration based on the molecular clutch mechanism
S. Campbell, R. Zitnay, M. Mendoza, T. C. Bidone
The paper develops a computational model to study how ECM microstructure affects 3D cell migration through force-sensitive molecular clutches, finding that pore size and porosity influence migration speed.
bioRxiv · Sep 29, 2021 · PreprintBiophysics