The large terminase DNA packaging motor grips DNA with its ATPase domain for cleavage by the flexible nuclease domain
B. J. Hilbert, J. A. Hayes, N. P. Stone, R.-G. Xu, B. A. Kelch
This study investigates how the large terminase protein binds and cleaves DNA during viral genome packaging, revealing the ATPase domain's role in DNA binding and the nuclease domain's role in cleavage.
bioRxiv · Oct 19, 2016Biochemistry