Egr1 loss-of-function promotes beige adipocyte differentiation and activation specifically in inguinal subcutaneous white adipose tissue
Marianne Bléher, Berbang Meshko, Isabelle Cacciapuoti, Rachel Gergondey, Yoann Kovacs, Delphine Duprez, Aurore L’honoré, Emmanuelle Havis
This paper shows that Egr1 loss-of-function promotes beige adipocyte differentiation and activation specifically in inguinal subcutaneous white adipose tissue, leading to increased Ucp1 expression and a metabolic shift to a more brown-like state.
Scientific Reports · Sep 28, 2020Peer-reviewedDevelopmental Biology