Isabelle Cacciapuoti

This paper shows that Egr1 loss-of-function promotes beige adipocyte differentiation and activation specifically in inguinal subcutaneous white adipose tissue, leading to increased Ucp1 expression and a metabolic shift to a more brown-like state.

This study identifies mechanical and molecular factors influencing tendon differentiation of C3H10T1/2 cells in 2D and 3D cultures, showing that silicone substrates and 3D fibrin environments enhance tendon marker expression.