Marianne Bléher

This paper shows that Egr1 loss-of-function promotes beige adipocyte differentiation and activation specifically in inguinal subcutaneous white adipose tissue, leading to increased Ucp1 expression and a metabolic shift to a more brown-like state.

This study shows that Egr1 deficiency promotes browning of inguinal white adipose tissue in mice by enhancing Ucp1 expression and reducing extracellular matrix genes.