Ceramide Synthases Regulate Myristate-Induced Intestinal IRE1α Activation
Chelsea L. Doll, Mary R. Gordon, Marco Padilla‐Rodriguez, Eugene Jap, Paul Antwi Boasiako, Marilyn T. Marron, Brandon K Dahl, Keila S. Espinoza, Drew M Seiser, Rachel J Ren, Curtis A. Thorne, Justin M. Snider, Ashley J. Snider
This study shows myristate induces ER stress via ceramide synthases, and restoring sphingoid bases reduces intestinal ER stress.
bioRxiv · May 31, 2026 · PreprintMolecular Biology