Ashley J. Snider

This study shows myristate induces ER stress via ceramide synthases, and restoring sphingoid bases reduces intestinal ER stress.

This study shows that loss of acid ceramidase in myeloid cells reduces inflammation and protects from chronic colitis in IL10-deficient mice by impairing immune cell recruitment and altering sphingolipid metabolism.

This study identifies nSMase2 as a critical mediator of Doxorubicin-induced cardiotoxicity and shows its loss protects against cardiac damage.