Intravenous Administration of Serotonergic Psychedelics Produce Short-lasting Changes in Sleep-Wake Behavior and High Gamma Functional Connectivity in Rats
Nicholas Kolbman, Emma R. Huels, Amanda G. Nelson, Rachel Summerfield, Kanakaharini Byraju, Trent Groenhout, Tiecheng Liu, Anthony G. Hudetz, Giancarlo Vanini, Dinesh Pal
This study examines the effects of intravenous psilocybin and DMT on sleep-wake states and EEG functional connectivity in rats, finding short-term changes in sleep patterns and increased high gamma coherence.
bioRxiv · Oct 12, 2025 · PreprintNeuroscience