Author

Emma R. Huels

University of MichiganORCID 0000-0002-7147-7979Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:electronic health records· 4 Organism:rat· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Amanda G. NelsoniD· 3 shared Dinesh PaliD· 3 shared George A. MashouriD· 3 shared Nicholas KolbmaniD· 2 shared Tiecheng LiuiD· 2 shared Trent GroenhoutiD· 2 shared Abdallah M. ZeidiD· 1 shared Abhinav Raghu· 1 shared

Activity by Year

2021-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

Amanda G. NelsonORCID

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Author profile →

4 papers

Recent·Most cited

Neurochemical and Neurophysiological Effects of Intravenous Administration of N,N-Dimethyltryptamine in Rats

Nicolas G. Glynos, Emma R. Huels, Trent Groenhout, Abhinav Raghu, Amanda G. Nelson, Youngsoo Kim, Abdallah M. Zeid, Tiecheng Liu, George A. Mashour, Robert T. Kennedy, Dinesh Pal

This study investigates the neurochemical and neurophysiological effects of DMT in rats, finding dose-dependent increases in serotonin and dopamine and changes in EEG power and functional connectivity.

Journal of Neuroscience · Dec 19, 2025Peer-reviewedNeuroscience

Intravenous Administration of Serotonergic Psychedelics Produce Short-lasting Changes in Sleep-Wake Behavior and High Gamma Functional Connectivity in Rats

Nicholas Kolbman, Emma R. Huels, Amanda G. Nelson, Rachel Summerfield, Kanakaharini Byraju, Trent Groenhout, Tiecheng Liu, Anthony G. Hudetz, Giancarlo Vanini, Dinesh Pal

This study examines the effects of intravenous psilocybin and DMT on sleep-wake states and EEG functional connectivity in rats, finding short-term changes in sleep patterns and increased high gamma coherence.

bioRxiv · Oct 12, 2025 · PreprintNeuroscience

Psychedelic-mediated Reversal of General Anesthesia and Restoration of Brain Dynamics in Rat

Emma R. Huels, Nicholas Kolbman, Christopher W. Fields, Amanda G. Nelson, Hazel Jackson, Tiecheng Liu, George A. Mashour, Dinesh Pal

This study shows that DOI, a serotonergic psychedelic, can reverse general anesthesia and restore brain dynamics in rats, as evidenced by behavioral arousal and recovery of functional connectivity.

bioRxiv · Jan 22, 2025 · PreprintNeuroscience

Neural correlates of the shamanic state of consciousness

Emma R. Huels, Hyoungkyu Kim, UnCheol Lee, Tarik Bel‐Bahar, Angelo V. Colmenero, Amanda Nelson, Stefanie Blain‐Moraes, George A. Mashour, Richard Edmund Harris

This study investigates the neural correlates of the shamanic state of consciousness using EEG in practitioners and controls, finding distinct brain activity patterns compared to psychedelic-induced states.

Frontiers in Human Neuroscience · Mar 18, 2021Peer-reviewedNeuroscience