An Ovol1 Variant in Endothelial Cells Regulates Slug and is Essential for Pathological Angiogenesis
Kapil Thapa, Brandon Burow, Melody C Baddoo, Marshall J Peelle, Haiden Citron, Rajan K C, Shawn Sutherland, Christopher J Hatch, Nadia Crawford, Ava Karp, Stryder M Meadows, Daniel P Howsmon, Brent A Stanfield, Kelly Subramanian, Christopher C Hughes, Jennifer S Fang
This study identifies an endothelial-specific Ovol1 variant that upregulates Slug and drives pathological angiogenesis in disease models.
bioRxiv · Nov 3, 2026 · PreprintCell Biology