Stryder M. Meadows

This study identifies an endothelial-specific Ovol1 variant that upregulates Slug and drives pathological angiogenesis in disease models.

This study investigates how caveolae are spatially organized in endothelial cells during angiogenesis and identifies their predictive role in vascular stability.

This paper develops new mouse models of HHT by inducing somatic LOH mutations in endothelial cells to study disease progression and therapeutic responses.

This study shows that loss of Zmiz1 in mice causes brain abnormalities and autistic-like behaviors, with molecular changes affecting neurogenesis and synaptic signaling.

This study uses scRNA-seq to identify decreased retinoic acid signaling in endothelial cells post-Glenn surgery, linking it to accelerated PAVM progression and suggesting dietary vitamin A modification as a potential therapeutic strategy.

This study shows that Zmiz1 is essential for both normal and abnormal angiogenesis in the retina, affecting vascular development and regression in mice.

This study identifies Zmiz1 as a regulator of lymphatic endothelial cell function and Prox1 expression, showing its role in lymphatic vessel development and valve formation.

This study shows ATP6AP2 is essential for endothelial cell polarity and extracellular matrix production during both normal and disease-related blood vessel growth.