Neuron specific ablation of eIF5A or deoxyhypusine synthase leads to impairment in development and cognitive functions in mice
Rajesh Kumar Kar, Ashleigh S. Hanner, Matthew F. Starost, Danielle Springer, Teresa L. Mastracci, Raghavendra G. Mirmira, Myung Hee Park
This study shows that deleting eIF5A or DHPS in mice causes brain development issues and cognitive impairments, with DHPS knockouts showing more severe effects.
bioRxiv · May 11, 2021 · PreprintNeuroscience