Time-Resolved Single-Molecule FRET Reveals Length-Dependent Nucleosome Decompaction by Poly(ADP-ribose)
Tianjin Yang, Soundhararajan Gopi, Louise Pinet, Sebastian Simoni, Ralph Imhof, Daniel Nettels, Matthias Altmeyer, Robert B. Best, Benjamin Schuler
This study uses time-resolved single-molecule FRET to show that PAR length determines nucleosome decompaction efficiency and reversibility.
bioRxiv · Feb 27, 2026 · PreprintBiophysics