Hsa-MiR-483 -3p Regulates the Extracellular Matrix Proteins via TGFbeta2/SMAD4 Signaling in the Glucocorticoid-responsive Human Trabecular Meshwork Cells
Ravinarayanan Haribalaganesh, Rajendrababu Sharmila, Ramasamy Krishnadas, Colin Eric Willoughby, Srinivasan Senthilkumari
This study shows that miR-483-3p reduces ECM production via SMAD4/TGFβ2 signaling in glucocorticoid-responsive HTM cells, suggesting therapeutic potential for steroid-induced glaucoma.
Cell and Tissue Research · Jun 5, 2025Peer-reviewedCell Biology