Bharanidharan Devarajan

A Comparative Genome-wide Transcriptome Analysis of Glucocorticoid Responder and Non-Responder Primary Human Trabecular Meshwork Cells

This study compares gene expression in GC-responsive and non-responsive HTM cells to identify molecular targets for treating GC-induced ocular hypertension.

Identification of Dysregulated Pathways and key genes in Human Retinal Angiogenesis using Microarray Metadata

The paper identifies dysregulated pathways and key genes in retinal angiogenesis using microarray data from PDR, ROP, and nAMD, revealing cytokine-cytokine receptor interaction as a significant pathway.

Whole Exome Sequencing identifies multiple pathogenic variants in a large south Indian family with Primary Open Angle Glaucoma

The paper uses whole exome sequencing to identify pathogenic variants in a South Indian family with Primary Open Angle Glaucoma, finding variants in RPGRIP1 and ARHGEF40 that co-segregate with the disease.

Comparative Analysis of non-coding small-RNAs in Pseudomonas aeruginosa Keratitis Strains with Different Antibiotic Susceptibility

This study identifies sRNA SPA0023 in MDR/XDR Pseudomonas aeruginosa keratitis strains and links its negative regulation of OprD to imipenem resistance.

Performance Assessment of Variant Calling Pipelines using Human Whole Exome Sequencing and Simulated data

This study evaluates 20 variant calling pipelines using WES data and simulated datasets to identify the best combinations for detecting SNVs and InDels.