PREFRONTAL CORRELATES OF FEAR GENERALIZATION DURING ENDOCANNABINOID DEPLETION
Luis E. Rosas-Vidal, Saptarnab Naskar, Leah M. Mayo, Irene Perini, Rameen Masroor, Megan Altemus, Liorimar Ramos-Medina, S. Danyal Zaidi, Hilda Engelbrektsson, Puja Jagasia, Markus A Heilig, Sachin Patel
This study shows that 2-AG levels inversely correlate with fear generalization in both mice and humans, suggesting a role in fear discrimination.
Journal of Clinical Investigation · Mar 27, 2025Peer-reviewedNeuroscience