Evidence that the cell cycle is a series of uncoupled, memoryless phases
Hui Xiao Chao, Randy I Fakhreddin, Hristo K Shimerov, Katarzyna M. Kedziora, Rashmi J. Kumar, Joanna Perez, Juanita C. Limas, Gavin D. Grant, Jeanette Gowen Cook, Gaorav P. Gupta, Jeremy E. Purvis
The paper quantifies cell cycle phase durations in human cells and finds they are memoryless and uncoupled, with a mathematical model explaining their independence and potential coupling under dysfunction.
Molecular Systems Biology · Mar 1, 2019Peer-reviewedSystems Biology