Gavin D. Grant

The paper quantifies cell cycle phase durations in human cells and finds they are memoryless and uncoupled, with a mathematical model explaining their independence and potential coupling under dysfunction.

The paper investigates Cdt1 variants associated with Meier-Gorlin syndrome and a Drosophila allele to uncover their effects on MCM loading, Cyclin/CDK interactions, and genome replication.

The Cell Cycle Browser allows users to visualize, simulate, and perturb cell cycle progression using real-time reporter data from human cells.

This study examines how DNA damage checkpoints affect cell cycle phase transitions, revealing phase-specific differences in checkpoint sensitivity and cell fate outcomes.