ARF6 controls VSMC cell phenotypic switching upon lipid stimulation to promote inflammatory signaling contributing to the progression of atherosclerosis
Emilie Fiola-Masson, Shirley L. Campbell, Véronique Laplante, Rania Lejri, Yasunori Kanaho, Jean‐François Gauchat, Marc J. Servant, Audrey Claing
This study shows that ARF6 promotes VSMC phenotypic switching and inflammatory signaling in atherosclerosis by modulating lipid uptake, cytokine production, and inflammatory pathways.
bioRxiv · Sep 16, 2025 · PreprintBiochemistry