Author

Marc J. Servant

Université de MontréalORCID 0000-0003-2014-4127Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Florence Dô· 2 shared Ana Claudia AndradeiD· 1 shared Audrey ClaingiD· 1 shared Baptiste DemeyiD· 1 shared Charlotte GirondeliD· 1 shared David N. HuynhiD· 1 shared Émile LacasseiD· 1 shared Emilie Fiola-MassoniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

Florence Dô

Mutual co-authors in cluster

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 9, 2026

The orphan receptor IL-17RD is a negative regulator of RIG-I-like receptor-dependent antiviral innate immunity and restrains SARS-CoV-2-induced lung inflammation

Firas El-Mortada, Jiunn Roy, Charlotte Girondel…·Marc J. Servant

This study identifies IL-17RD as a negative regulator of RIG-I-like receptor-dependent antiviral immunity, showing it limits SARS-CoV-2-induced lung inflammation.

DOI 10.64898/2026.09.01.747870

humanbulk RNA-seq

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Molecular BiologyCellsPeer-reviewedJan 23, 2026

Early IKKb-dependent anabolic signature governs vascular smooth muscle cells fate and abdominal aortic aneurysm development

Priscilla Doyon, Özge Kizilay Mancini, Florence Dô…·Marc J. Servant

This study identifies an early IKKβ-dependent anabolic signature in vascular smooth muscle cells that drives abdominal aortic aneurysm development.

1 citation

mousebulk RNA-seq

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BiochemistrybioRxivPreprintSep 16, 2025

ARF6 controls VSMC cell phenotypic switching upon lipid stimulation to promote inflammatory signaling contributing to the progression of atherosclerosis

Emilie Fiola-Masson, Shirley L. Campbell, Véronique Laplante…·Audrey Claing

This study shows that ARF6 promotes VSMC phenotypic switching and inflammatory signaling in atherosclerosis by modulating lipid uptake, cytokine production, and inflammatory pathways.

DOI 10.1101/2025.09.16.676422

mousehuman

𝕏 PostBluesky