A Multi-Omic Phenobank Reveals Axes of Glioblastoma Growth, Invasion, and Therapeutic Vulnerability
Cecilia C. Krona, Soumi Kundu, Emil Rosén, Filippa Kruse, Madeleine Skeppås, Haris Babačić, Ida Larsson, Ludmila Elfineh, Maya Jeje Schuan Lü, Maria Escriva Conde, Ramy Elgendy, Zankruti Dave, Milena Doroszko, Katrin Rut-Halldorsdottir, Xiaofang Cao, , Sven Nelander
The paper establishes a multi-omic PDX resource linking GBM invasion phenotypes to molecular programs and therapeutic responses, identifying two invasion modes and a neurodevelopmental factor associated with tumor growth and survival.
Neuro-Oncology · Oct 12, 2026Peer-reviewedCancer Biology