Germline ERBB3 mutation in familial non-small cell lung carcinoma: expanding the role of the ErbB family in oncogenesis.
Aideen M McInerney-Leo, Hui Yi Chew, Po-Ling Inglis, Paul J. Leo, Shannon R. Joseph, Caroline Louise Cooper, Satomi Okano, Tim Hassall, Lisa K. Anderson, Rayleen Bowman, Michael R. Gattas, Jessica E Harris, Mhairi S. Marshall, Janet G. Shaw, Lawrie Wheeler, , Emma L. Duncan
The paper identifies a germline ERBB3 mutation in a family with hereditary non-small cell lung cancer, showing it drives oncogenesis through altered signaling.
Human Molecular Genetics · Jul 16, 2021Peer-reviewedGenomics