Spatial Transcriptomic Sequencing of a DIPG-infiltrated Brainstem reveals Key Invasion Markers and Novel Ligand-Receptor Pairs contributing to Tumour to TME Crosstalk
Anja Kordowski, Onkar Mulay, Xiao Tan, Tuan Vo, Ulrich Baumgartner, Mellissa K. Maybury, T. E. G. Hassall, Brandon J. Wainwright, Lachlan Harris, Quan Hoang Nguyen, Bryan W. Day
This study uses spatial transcriptomics to analyze a DIPG-infiltrated brainstem, identifying invasion markers and ligand-receptor pairs involved in tumour-TME crosstalk.
bioRxiv · May 7, 2024 · PreprintCancer Biology