Author

Lawrie Wheeler

Translational Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:whole-exome sequencing· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Organism:mouse· 1

Frequent Co-Authors

Lisa K. AndersoniD· 3 shared Matthew Arthur BrowniD· 3 shared Aideen M McInerney-LeoiD· 2 shared Emma L. DuncaniD· 2 shared Mhairi S. Marshall· 2 shared Paul J. LeoiD· 2 shared Alex William HewittiD· 1 shared Alice PébayiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersGenomics

Lisa K. AndersonORCID

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Author profile →

3 papers

Recent·Most cited

Germline ERBB3 mutation in familial non-small cell lung carcinoma: expanding the role of the ErbB family in oncogenesis.

Aideen M McInerney-Leo, Hui Yi Chew, Po-Ling Inglis, Paul J. Leo, Shannon R. Joseph, Caroline Louise Cooper, Satomi Okano, Tim Hassall, Lisa K. Anderson, Rayleen Bowman, Michael R. Gattas, Jessica E Harris, Mhairi S. Marshall, Janet G. Shaw, Lawrie Wheeler, , Emma L. Duncan

The paper identifies a germline ERBB3 mutation in a family with hereditary non-small cell lung cancer, showing it drives oncogenesis through altered signaling.

Human Molecular Genetics · Jul 16, 2021Peer-reviewedGenomics

A rare SMAD9 mutation identifies the BMP signalling pathway as a potential osteoanabolic target

Celia Louise Gregson, Dylan J. M. Bergen, Paul Leo, Richard Barry Sessions, Lawrie Wheeler, April E. Hartley, Scott E. Youlten, Peter Ian Croucher, Aideen M McInerney-Leo, William Duncan Fraser, JONATHAN C. Y. TANG, Lisa K. Anderson, Mhairi S. Marshall, Leon Mieczyslaw Sergot, Lavinia Paternoster, , Emma L. Duncan

A rare SMAD9 mutation is linked to high bone mass, suggesting the BMP pathway as a potential osteoanabolic target.

bioRxiv · Feb 25, 2019 · PreprintGenetics

Longitudinal expression profiling of CD4+ and CD8+ cells in patients with active to quiescent Giant Cell Arteritis

Elisabeth De Smit, Samuel W. Lukowski, Lisa K. Anderson, Anne Senabouth, Kaisar Dauyey, Sharon Song, Bruce D. Wyse, Lawrie Wheeler, Christine Y Chen, Khoa N. Cao, Amy Wong Ten Yuen, Neil H. Shuey, Linda Clarke, Maria Isabel G. Lopez Sanchez, Sandy S. C. Hung, , Joseph E. Powell

This study identifies transcriptomic biomarkers in CD4+ and CD8+ T cells from GCA patients over 12 months, revealing gene-phenotype associations and potential prognostic indicators.

BMC Medical Genomics · Jul 23, 2018Peer-reviewedGenomics