Flipping the odds of drug development success through human genomics
Aroon Dinesh Hingorani, Valerie Kuan, Chris Finan, Felix Alexander Krüger, Anna Gaulton, Sandesh Chopade, Reecha Sofat, Raymond J. MacAllister, John P. Overington, Harry Hemingway, Spiros Denaxas, David Prieto‐Merino, Juan Pablo Casas
The paper discusses how integrating druggable target genes with disease susceptibility genes can improve drug development success rates by reducing target specification errors.
bioRxiv · Jul 30, 2017 · PreprintGenomics