Author

Rays H.Y. Jiang

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Cell Biology· 1

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Research Focus:drug response / drug discovery· 1 Organism:plant (other)· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

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Andrea Rivero· 1 shared ChengQi Wang· 1 shared Dennis E. KyleiD· 1 shared Roman ManetschiD· 1 shared Sasha Siegel· 1 shared Swamy R. Adapa· 1 shared

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2017-2017 · peak 1/yr

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1 shared paperCell Biology

Andrea Rivero

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Recent·Most cited

Mitochondrial heteroplasmy is responsible for Atovaquone drug resistance in Plasmodium falciparum

Sasha Siegel, Andrea Rivero, Swamy R. Adapa, ChengQi Wang, Roman Manetsch, Rays H.Y. Jiang, Dennis E. Kyle

This study identifies mitochondrial heteroplasmy as the cause of Atovaquone resistance in Plasmodium falciparum, showing pre-existing Y268S alleles in the mitochondrial genome contribute to drug resistance.

bioRxiv · Dec 10, 2017 · PreprintCell Biology