RadD from Fusobacterium nucleatum Engages NKp46 to Promote Antitumor Cytotoxicity
Ahmed Rishiq, Johanna Galaski, Reem Bsoul, Mingdong Liu, Rema Darawshe, Renate Lux, Gilad Bachrach, Ofer Mandelboim
The paper identifies RadD from Fusobacterium nucleatum as a ligand for NKp46, showing it enhances NK cell cytotoxicity and suppresses tumor growth in head and neck cancers.
bioRxiv · Jul 26, 2025Immunology