Nectriatides with no antifungal activity bind to ergosterol and potentiate the antifungal activity of amphotericin B against Candida albicans
Keisuke Kobayashi, Ryosuke Miyake, Kenichiro Nagai, Yukino Sato, Reiko Seki, Kumiko Sakai‐Kato, Shinichi Nishimura, Taichi Ohshiro, Hiroshi Tomoda
The paper shows nectriatide-based compounds bind to ergosterol on Candida albicans membranes, enhancing amphotericin B's antifungal effect.
ACS Omega · May 13, 2026Peer-reviewedMicrobiology