Lipid chlorination mobilizes Neutrophil Elastase to initiate NETosis
Volker Brinkmann, Christian Goosmann, Renate Krueger, Horst von Bernuth, Michael Mülleder, Kathrin Textoris‐Taube, Brenda Moreira-Walsh, David A. Ford, A Foti
The paper shows lipid chlorination by MPO-derived hypochlorous acid enables NE release from granules, initiating NETosis.
bioRxiv · Jul 11, 2026 · PreprintImmunology