Reduction in activity and abundance of mitochondrial electron transport chain supercomplexes in pulmonary hypertension-induced right ventricular dysfunction
Wenzhuo Ma, Peng Zhang, Alexander Vang, Alexsandra Zimmer, Scarlett Huck, Preston Nicely, Eric Wang, Thomas J Mancini, Joseph Owusu-Sarfo, Clarissa F. Cavarsan, Andriy E. Belyvech, Kenneth S. Campbell, Dmitry Terentyev, Gaurav Choudhary, Richard T. Clements
This study shows reduced mitochondrial supercomplex activity and abundance in pulmonary hypertension-induced right ventricular dysfunction in rats and humans.
bioRxiv · Mar 8, 2024 · PreprintPathology