Clarissa F. Cavarsan

Reduction in activity and abundance of mitochondrial electron transport chain supercomplexes in pulmonary hypertension-induced right ventricular dysfunction

This study shows reduced mitochondrial supercomplex activity and abundance in pulmonary hypertension-induced right ventricular dysfunction in rats and humans.

Inhibitory interneurons show early dysfunction in a SOD1 mouse model of amyotrophic lateral sclerosis

This study shows inhibitory interneurons in SOD1 mice exhibit early excitability and morphology changes, suggesting they contribute to ALS pathogenesis before motor neuron damage.

Enhanced nociceptor sprouting in a rabbit model of cerebral palsy

This study investigates how prenatal hypoxia-ischemia injury affects spinal nociceptive circuitry in rabbits, finding increased nociceptive afferents and enhanced mechanical and thermal sensitivity.

Altered motoneuron properties contribute to motor deficits in a rabbit hypoxia ischemia model of cerebral palsy

This study investigates how altered spinal motoneuron properties contribute to motor deficits in a rabbit hypoxia-ischemia model of cerebral palsy, finding significant physiological differences between affected and unaffected groups.