Src/Fas2-dependent Ephrin phosphorylation initiates Eph/Ephrin reverse signaling through Rac1 to shape columnar units in the fly brain
Miaoxing Wang, Xujun Han, Yunfei Lee, Rie Takayama, Makoto Sato
This study identifies a bi-directional Ephrin/Eph signaling mechanism involving Src/Fas2-dependent Ephrin phosphorylation and Rac1 to regulate columnar neuron morphology and positioning in the fly brain.
Science Advances · Aug 13, 2025Peer-reviewedDevelopmental Biology