Author

Xujun Han

Kanazawa UniversityORCID 0000-0002-4049-4039Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Borui Li· 1 shared Dominic Chih‐Cheng VooniD· 1 shared Hiroyuki ManoiD· 1 shared Holger FlechsigiD· 1 shared Katsuya SakaiiD· 1 shared Koji FukudaiD· 1 shared Kunio MatsumotoiD· 1 shared Makoto SatoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Borui Li

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2 papers

Recent·Most cited

Src/Fas2-dependent Ephrin phosphorylation initiates Eph/Ephrin reverse signaling through Rac1 to shape columnar units in the fly brain

Miaoxing Wang, Xujun Han, Yunfei Lee, Rie Takayama, Makoto Sato

This study identifies a bi-directional Ephrin/Eph signaling mechanism involving Src/Fas2-dependent Ephrin phosphorylation and Rac1 to regulate columnar neuron morphology and positioning in the fly brain.

Science Advances · Aug 13, 2025Peer-reviewedDevelopmental Biology

High-Speed AFM Reveals IDR-Mediated Structural Plasticity of EML4-ALK Modulated by ALK Inhibitors

Xujun Han, Noriyuki Kodera, Neval Yilmaz, Katsuya Sakai, Sachiko Arai, Borui Li, Ryu Imamura, Dominic Chih‐Cheng Voon, Koji Fukuda, Shigeki Nanjo, Holger Flechsig, Hiroyuki Mano, Kunio Matsumoto, Seiji Yano

The paper uses high-speed AFM to study how ALK inhibitors affect the structure and dynamics of EML4-ALK variants, revealing IDR-mediated plasticity and resistance mechanisms.

bioRxiv · Aug 7, 2025 · PreprintCancer Biology