Author

Rieke Sprengel

Freie Universität Berlin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alexander SonntagiD· 1 shared Franziska SchanbacheriD· 1 shared Giorgia Del FaveroiD· 1 shared Johannes Kollatz· 1 shared Mathias WinterhalteriD· 1 shared Maximilian JobstiD· 1 shared Mohamad SaoudiD· 1 shared Rebeca Ruiz· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alexander SonntagORCID

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1 paper

Recent·Most cited

Aetokthonotoxin, the causative agent of vacuolar myelinopathy, uncouples oxidative phosphorylation due to protonophore activity

Valerie I. C. Rebhahn, Mohamad Saoud, Mathias Winterhalter, Franziska Schanbacher, Maximilian Jobst, Rebeca Ruiz, Alexander Sonntag, Johannes Kollatz, Rieke Sprengel, Stephen F. Donovan, Giorgia Del Favero, Robert Rennert, Timo H. J. Niedermeyer

This study identifies Aetokthonotoxin as a protonophore that uncouples oxidative phosphorylation, leading to ATP depletion and neurotoxic effects in wildlife.

Chemical Research in Toxicology · Jul 25, 2025Peer-reviewedPharmacology & Toxicology