TcCARP3 modulates compartmentalized cAMP signals involved in osmoregulation, infection of mammalian cells, and colonization of the triatomine vector in the human pathogen Trypanosoma cruzi
Joshua Carlson, Milad Ahmed, Riley Hunter, Syeda Farjana Hoque, Joshua B. Benoit, Miguel Ángel Chiurillo, Noelia Marina Lander
This study identifies TcCARP3 as a regulator of cAMP signaling in Trypanosoma cruzi, essential for osmoregulation, host cell invasion, and vector colonization.
mBio · May 23, 2025Peer-reviewedMicrobiology