Cyclic AMP compartmentalization drives signal specificity to control vector colonization and mammalian host infection by American trypanosomes
Milad Ahmed, Joshua Carlson, Asima Das, Syeda Farjana Hoque, Joshua B. Benoit, Miguel Ángel Chiurillo, Noelia Marina Lander
This study identifies two cAMP microdomains in Trypanosoma cruzi, showing their distinct roles in parasite survival and infection.
PLoS Pathogens · Jun 29, 2026Peer-reviewedCell Biology