Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure
Zeran Li, Jorge L. Del‐Aguila, Umber Dube, John Budde, Rita Martinez, Kathleen Black, Qingli Xiao, Nigel J. Cairns, The Dominantly Inherited Alzheimer Network (DIAN), Joseph D. Dougherty, Jin‐Moo Lee, John C. Morris, Randall John Bateman, Celeste M M. Karch, Carlos Cruchaga, Oscar Harari
This study identifies how genetic risk variants for Alzheimer's disease affect cerebral cortex cell-type proportions in bulk RNA-seq data using digital deconvolution.
Genome Medicine · Jun 6, 2018Peer-reviewedGenetics