Author

Kathleen Black

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Carlos CruchagaiD· 2 shared John BuddeiD· 2 shared John C. MorrisiD· 2 shared Jorge L. Del‐AguilaiD· 2 shared Oscar HarariiD· 2 shared Randall John BatemaniD· 2 shared Alison GoateiD· 1 shared Anne M. FaganiD· 1 shared

Activity by Year

2017-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersGenetics

Carlos CruchagaORCID

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2 papers

Recent·Most cited

Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure

Zeran Li, Jorge L. Del‐Aguila, Umber Dube, John Budde, Rita Martinez, Kathleen Black, Qingli Xiao, Nigel J. Cairns, The Dominantly Inherited Alzheimer Network (DIAN), Joseph D. Dougherty, Jin‐Moo Lee, John C. Morris, Randall John Bateman, Celeste M M. Karch, Carlos Cruchaga, Oscar Harari

This study identifies how genetic risk variants for Alzheimer's disease affect cerebral cortex cell-type proportions in bulk RNA-seq data using digital deconvolution.

Genome Medicine · Jun 6, 2018Peer-reviewedGenetics

Polygenic Risk Score of Sporadic Late Onset Alzheimer Disease Reveals a Shared Architecture with the Familial and Early Onset Forms

Carlos Cruchaga, Jorge L. Del‐Aguila, Benjamin A. Saef, Kathleen Black, María Victoria Fernández, John Budde, Laura Ibáñez, Yuetiva K. Deming, Manav Kapoor, Giuseppe Tosto, Richard P Mayeux, David M. Holtzman, Anne M. Fagan, John C. Morris, Randall John Bateman, , Oscar Harari

The paper constructs polygenic risk scores for sporadic late-onset Alzheimer's Disease and finds shared genetic architecture with familial and early-onset forms, showing varying odds ratios across cohorts.

Alzheimer s & Dementia · Sep 21, 2017Peer-reviewedGenetics